期刊
ARCHIVES OF BIOLOGICAL SCIENCES
卷 66, 期 4, 页码 1441-1446出版社
INST BIOLOSKA ISTRAZIVANJA SINISA STANKOVIC
DOI: 10.2298/ABS1404441V
关键词
Cyanobacteria; Aphanothece halophytica; microcystin; serum enzymes; ELISA
类别
资金
- UGC, New Delhi, India
Aphanothece halophytica is an extremely saline cyanobacterium. This study investigates the toxic nature of the organism and presents the first report of hepatotoxic cyclic heptapeptide microcystin analogs. The activity of the crude extract was investigated in mice. Results showed acute toxicity with mice death at about 4 h. Histopathological examination indicated massive alveolar hemorrhage and extensive congestion in liver cells. Increases in the levels of serum enzymes, i. e., AST (aspartate aminotransferase), ALT (alanine aminotransferase) and LDH (lactate dehydrogenase), provide further evidence of cell injury. An ELISA-based immunological detection kit confirmed the presence of microcystin analogs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据