期刊
ARCHIVES OF PHARMACAL RESEARCH
卷 27, 期 3, 页码 300-304出版社
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/BF02980064
关键词
Parthenocissus tricuspidata; caffeic acid derivatives; antioxidant activities
Five caffeic acid derivatives; methyl ester of caffeoylglycolic acid (1), dimethyl ester of caffeoyltartaric acid (2), dimethyl ester of caffeoyltartronic acid (3), monomethyl ester of caffeoyltartronic acid (4), methyl ester of caffeic acid (5), and some other secondary metabolites including; quercetin, quercetin 3-O-beta-D-glucuronide methyl ester, kaempferol, 3,5,7,4'-O-tetramethylkaempferol, beta-sitosterol glucoside, 2alpha-hydroxyursolic acid and 2,24-dihydroxyursolic acid, have been isolated and characterized. All the isolated compounds were characterized with the help of NMR spectroscopy and mass spectrometry. Structure of compound 3 was also confirmed by a single X-ray crystallographic technique. Isolates were evaluated for antioxidant activities and most of the tested compounds were found to be potent in DPPH free radical scavenging (IC50 = 4.56-14.17 mug/mL) and superoxide anion scavenging (IC50 = 0.58-7.39 mug/mL) assays.
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