期刊
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
卷 531, 期 1-2, 页码 24-33出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.abb.2012.10.003
关键词
Unfolded state dynamics; Polypeptide chain collapse; Molten globule; Folding mechanisms; Hydrophobic collapse
资金
- Government of India
- Tata Institute of Fundamental Research
- Department of Biotechnology
- Department of Science and Technology, Government of India
Polypeptide chain collapse is an integral component of a protein folding reaction. In this review, experimental characterization of the interplay of polypeptide chain collapse, secondary structure formation, consolidation of the hydrophobic core and the development of tertiary interactions, is scrutinized. In particular, the polypeptide chain collapse reaction is examined in the context of the three phenomenological models of protein folding - the hydrophobic collapse model, the framework model and the nucleation condensation model - which describe different ways by which polypeptide chains are able to fold in biologically relevant time-scales. (C) 2012 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据