期刊
BEHAVIOURAL BRAIN RESEARCH
卷 149, 期 2, 页码 113-122出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0166-4328(03)00221-3
关键词
schizophrenia; positive symptoms; negative symptoms; latent inhibition; attention
Latent inhibition (LI), retarded conditioning to a stimulus that has been previously repeatedly presented without reinforcement, was examined in young schizophrenics and normal controls using a within-subject visual search task. Healthy controls exhibited the usual LI effect. LI was potentiated in schizophrenics who simultaneously exhibited high levels of negative symptoms and low levels of positive symptoms. Schizophrenic groups with other combinations of positive and negative symptoms did not differ from controls. The pattern of data suggests that past inconsistencies in the LI-schizophrenia literature may be the result of opposing processes that are associated with positive and negative symptoms. (C) 2003 Elsevier B.V. All rights reserved.
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