期刊
BIOINFORMATICS
卷 20, 期 5, 页码 786-U719出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btg481
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Summary: Association studies may request more details of a specific haplotype. Haplotype-specific decay of linkage disequilibrium is such a crucial and versatile characteristic. It may be used, e.g. to search for signals of natural selection in a risk haplotype. Here, we present a web-based tool to explore the relationship between population frequency and extended linkage disequilibrium measured as haplotype homozygosity of observed haplotypes within a specified candidate region.
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