期刊
PHYTOCHEMISTRY
卷 65, 期 7, 页码 933-937出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2004.02.006
关键词
Discaria americana; Rhamnaceae; cyclic peptides; antibacterial activity
The isolation and structure determination of cyclic peptide alkaloids, discarine-M and discarine-N, along with seven known cyclic peptide alkaloids, adouetine-Y', franganine, frangulanine, discarines-A, -B, -C, and -D from the root bark of Discaria americana are described. Structures were determined spectroscopically, especially using 2D NMR spectroscopic analysis. The crude methanol extract, the basic ether extract, and the alkaloids 6 and 7 also weakly inhibited growth of gram-negative and gram-positive bacteria. (C) 2004 Elsevier Ltd. All rights reserved.
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