Purification, crystallization and preliminary X-ray diffraction analysis of human oncoprotein SET/TAF-1β

The human oncoprotein SET/TAF-1beta has been crystallized by the sitting-drop vapour-diffusion method using ammonium sulfate as a precipitant. The crystal belongs to space group C2, with unit-cell parameters a=119.6, b=62.8, c=61.0 Angstrom, beta=89.7degrees, and contains two molecules in the asymmetric unit. A complete data set was collected to 2.8 Angstrom resolution using synchrotron radiation.