期刊
PRENATAL DIAGNOSIS
卷 24, 期 4, 页码 265-275出版社
WILEY
DOI: 10.1002/pd.851
关键词
informed choice; decision analysis; prenatal testing; Down syndrome; patient attitudes
Objective To evaluate decision analysis as a technique to facilitate women's decision-making about prenatal diagnosis for Down syndrome using measures of effective decision-making. Design Randomised controlled trial in a UK hospital's prenatal diagnosis clinic. Intervention Routine versus routine consultation structured by decision analysis. Participants 117/132 women receiving a screen-positive maternal serum screening result participated (58 routine, 59 decision analysis). Methods Consultations were audio tape-recorded, transcribed and coded; questionnaires were completed after the consultation and one month later after receipt of a diagnostic test and/or the 19-week scan result. Main measures Test decision, subjective expected utilities, knowledge, informed decision-making, risk perception, decisional conflict, anxiety, perceived usefulness and directiveness of consultation information. Results 48/59 in the decision-aided group and 47/58 in the routine group underwent prenatal diagnosis. Informed decision-making was higher, perceived risk more realistic and decisional conflict over time lower in the decision analysis group. Decision analysis had no impact on knowledge or SEU scores, and was no more or no less directive, useful or anxiety provoking than the routine care. Consultations were six minutes longer. Conclusions Decision analysis consultations enable women to make more informed prenatal diagnosis decisions. Professionals will need training to use this technique effectively. Copyright (C) 2004 John Wiley Sons, Ltd.
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