期刊
NEUROIMAGE
卷 21, 期 4, 页码 1452-1463出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2003.11.022
关键词
fMRI; DTI; functional MRI; diffusion tensor imaging; visual system; optic; radiations; visual cortex
资金
- Multiple Sclerosis Society [748] Funding Source: Medline
A key objective in neuroscience is to improve our understanding of the relationship between brain function and structure. We investigated this in the posterior visual pathways of healthy volunteers by applying functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) with tractography. The optic radiations were segmented using the Probabilistic Index of Connectivity (PICo) tractography algorithm and extracted at several thresholds of connection confidence. The mean fractional anisotropy (FA) of the estimated tracts was found to correlate significantly with fMRI measures of visual cortex activity (induced by a photic stimulation paradigm). The results support the hypothesis that the visual cortical fMRI response is constrained by the external anatomical connections of the subserving optic radiations. (C) 2004 Elsevier Inc. All rights reserved.
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