期刊
TOXICOLOGY LETTERS
卷 149, 期 1-3, 页码 281-285出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.toxlet.2003.12.039
关键词
PCBs; dioxins; immune changes; pre-school children
类别
Perinatal exposure to PCBs and dioxins is associated with immune changes in healthy Dutch preschool children. To examine whether such effects persist into later childhood, we here report on the immunological effects of perinatal exposure to PCBs and dioxins in 167 Dutch children at school age. A higher postnatal PCB exposure was associated with a higher prevalence of recurrent middle ear infections and a higher prenatal PCB exposure with less shortness of breath with wheeze, as assessed by parent questionnaire. Our data indicate that, at environmental levels of these man made chemicals, subtle health effects may occur. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
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