4.8 Article

Neuronal activity related to reward value and motivation in primate frontal cortex

期刊

SCIENCE
卷 304, 期 5668, 页码 307-310

出版社

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1093223

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  1. NCRR NIH HHS [P41RR03631] Funding Source: Medline
  2. NEI NIH HHS [EY08098, EY11831] Funding Source: Medline
  3. NIMH NIH HHS [MH45156] Funding Source: Medline

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In several areas of the macaque brain, neurons. re during delayed-response tasks at a rate determined by the value of the reward expected at the end of the trial. The activity of these neurons might be related to the value of the expected reward or to the degree of motivation induced by expectation of the reward. We describe results indicating that the nature of reward-dependent activity varies across areas. Neuronal activity in orbitofrontal cortex represents the value of the expected reward, whereas neuronal activity in premotor cortex reflects the degree of motivation.

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