期刊
ADVANCED MATERIALS
卷 16, 期 8, 页码 699-+出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200305782
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Poly(ethylene glycol) (PEG)-covered hybrid particles (see Figure) of calcium phosphate (CaP), and plasmid DNA (pDNA) have been prepared in a size-controllable manner in the presence of a block copolymer. The particles show a substantial colloidal stability as well as tolerance of entrapped pDNA against nuclease attack in the medium, and achieve a significantly higher gene expression compared to conventional precipitates.
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