期刊
TETRAHEDRON LETTERS
卷 45, 期 17, 页码 3359-3362出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.03.020
关键词
combretastatin; 1,3-dipolar cycloaddition; nitrile oxide
A series of compounds related to combretastatin A-4, containing a five-membered heterocyclic ring interposed between the two phenyl groups have been Prepared. Synthetic approach involves 1,3-dipolar cycloaddition of various 3,4,5-trimethoxyphenyl units with an in situ generated nitrile oxide from a suitable aldoxime using sodium hypochlorite. Depending oil the nature of the dipolarophile, 3,5-diarylisoxazole derivatives obtained along with the 3,4-regioisomeric isomers. (C) 2004 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据