期刊
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
卷 36, 期 5, 页码 745-752出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biocel.2003.07.004
关键词
copper cells; acid-secreting cells; gastric parietal cells; labial gene
资金
- NIGMS NIH HHS [GM49301] Funding Source: Medline
Copper cells in the Drosophila larval midgut Were originally named for their ability to accumulate dietary copper. Recent studies have uncovered a number of intriguing similarities between copper cells and the acid-producing gastric parietal cells of the mammalian stomach. In addition to their shared roles in stomach acidification, they share a peculiar invaginated morphology in which the apical cell surface is buried deep within the cytoplasm. These shared properties of morphology and function portend the identification of shared molecular mechanisms that account for their specialized roles in digestive physiology. (C) 2003 Elsevier Ltd. All rights reserved.
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