期刊
PROCEEDINGS OF THE NUTRITION SOCIETY
卷 63, 期 2, 页码 331-335出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1079/PNS2004357
关键词
growth; hypertrophy; stretch
资金
- NIAMS NIH HHS [AR-45617] Funding Source: Medline
Repeated bouts of resistance exercise produce an increase in skeletal muscle mass. The accumulation of protein associated with the growth process results from a net increase in protein synthesis relative to breakdown. While the effect of resistance exercise on muscle mass has long been recognized, the mechanisms underlying the link between high-resistance contractions and the regulation of protein synthesis and breakdown are, to date, poorly understood. In the present paper skeletal muscle will be viewed as a mechanosensitive cell type and the possible mechanisms through which mechanically-induced signalling events lead to changes in rates of protein synthesis will be examined.
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