期刊
AQUATIC TOXICOLOGY
卷 152, 期 -, 页码 131-138出版社
ELSEVIER
DOI: 10.1016/j.aquatox.2014.03.029
关键词
beta-N-methylamino-L-alanine (BMAA); Dinoflagellates; Gymnodinium catenatum; Transitional water bodies; Cerastoderma edule; Bioaccumulation; Paralytic shellfish toxins; Portugal
资金
- Swedish Research Council, Formas
- Portuguese Foundation for Science and Technology (FCT) through the FCT Investigator Program [IF/00271/2013]
The neurotoxin beta-N-methylamino-L-alanine (BMAA) and its putative role in multiple neurodegenerative diseases have been intensely studied since 2005 when the toxin was discovered to be produced by worldwide-distributed cyanobacterial species inhabiting terrestrial, marine, brackish, and freshwater ecosystems. Recently, BMAA production was also associated with one eukaryotic group, namely, diatoms, raising questions about its production by other phytoplanktonic groups. To test for BMAA bioavailability in ecosystems where abundant phytoplanktonic blooms regularly occur, samples of filter-feeding shellfish were collected in two Portuguese transitional water bodies. BMAA content in cockles (Cerastoderma edule) collected weekly between September and November 2009 from Ria de Aveiro and at least once a month from May to November from Ria Formosa, fluctuated from 0.079 +/- 0.055 to 0.354 +/- 0.066 mu g/g DW and from below the limit of detection to 0.434 +/- 0.110 mu g/g DW, respectively. Simultaneously to BMAA occurrence in cockles, paralytic shellfish toxins were detected in shellfish as a result of Gymnodinium catenatum blooms indicating a possible link between this marine dinoflagellate and BMAA production. Moreover, considerable high BMAA levels, 0.457 +/- 0.186 mu g/g DW, were then determined in a laboratory grown culture of G. catenatum. This work reveals for the first time the presence of BMAA in shellfish from Atlantic transitional water bodies and consubstantiate evidences of G. catenatum as one of the main sources of BMAA in these ecosystems. (C) 2014 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据