New constituents of Artemisia monosperma

A new eudesmane sesquiterpene (1) and a C-10 diyne (2) were isolated from the aerial parts of Artemisia monosperma. The structures of these compounds were determined as rel-1beta, 3alpha, 6beta-trihydroxyeudesm-4-ene (1) and 1,3R,8R-trihydroxydec-9-en-4,6-yne (2) on the basis of spectral data interpretation. The absolute stereochemistry of 2 was determined using Mosher ester methodology in which the terminal primary hydroxyl group was first protected to simplify the stereochemical analysis.