期刊
TRENDS IN BIOCHEMICAL SCIENCES
卷 29, 期 5, 页码 257-264出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2004.03.003
关键词
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In the animal kingdom, the relationship between individuals and the environment is often modulated by chemical communication. In the olfaction of insects, small antennary proteins - such as odorant- and pheromone-binding proteins (OBPs and PBPs, respectively) and chemosensory proteins (CSP)- have been proposed to carry their ligand from the air-fluid interface to the olfactory receptors. Binding experiments and recent structural studies of three PBPs, an OBP and a CSP have illustrated their versatility and ability to accommodate ligands of different shapes and chemical structures. The role of these proteins - as simple transporters or receptor triggers - is still a matter of debate, but some recent data seem to support the latter.
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