期刊
MARINE BIOTECHNOLOGY
卷 6, 期 3, 页码 215-220出版社
SPRINGER
DOI: 10.1007/s10126-003-0010-z
关键词
antibiotic; production; marine natural products; cyclo(Phe-Pro)
资金
- NIGMS NIH HHS [S06 GM59833-01] Funding Source: Medline
Thirteen bacterial strains isolated from a sample of Ulva californica were cultured, extracted, and assayed for antibiotic activity. The target strains were 2 gram-positive isolates from the same algal sample. When cultured in monoculture, 2 of the 13 isolates produced extracts with antimicrobial activity. More significantly, one Bacillus isolate (UA-094) produced indole and cyclo(Phe-Pro) at active levels upon challenge with a different Bacillus target strain. These mildly antibiotic compounds were barely detectable in extracts without challenge. This technique of competitive induction and enhancement could be a valuable tool in the search for new antibiotics.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据