期刊
JOURNAL OF VIROLOGY
卷 78, 期 9, 页码 4914-4916出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.78.9.4914-4916.2004
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While recent studies have demonstrated that retroviral vectors can be used to stably express short hairpin RNA (shRNA) to inhibit gene expression, these studies have utilized replication-defective retroviruses. We describe the creation of a replication-competent, Gateway-compatible retroviral vector capable of expressing shRNA that inhibits the expression of specific genes.
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