期刊
NEUROSCIENCE LETTERS
卷 361, 期 1-3, 页码 241-244出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.neulet.2003.12.110
关键词
laser-evoked potentials; wavelet analysis; single-trial event-related potentials; A delta-fibres
The aim of this study was to identify EEG changes induced by Adelta-nociceptor activation in single trials. In a preliminary experiment, intense CO2 laser stimuli were delivered to the hand dorsum of five volunteers. The average amplitude of EEG epochs was estimated in the time-frequency (TF) domain using the continuous Morlet wavelet transform (CMT). The result was used as a TF filter enhancing Adelta-nociceptor induced EEG responses. In a second experiment, eight other subjects were delivered laser stimuli with six intensities. The CMT of each EEG epoch was Computed. After applying the TF filter, amplitudes within a predefined interval were summed. Whether this sum predicted the occurrence of Adelta-nociceptor activation was tested using the reaction-time to discriminate between Adelta- or C-fibre mediated detection. Results showed that this method accurately identified single-trial EEG responses to Adelta-nociceptor activation. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
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