期刊
NEUROSCIENCE LETTERS
卷 361, 期 1-3, 页码 147-150出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.neulet.2003.12.064
关键词
central and peripheral reactivity; chronic back pain; EEG; habituation; tension headache; pain threshold; peripheral measures
Sixteen chronic back pain (CBP) patients, 16 tension headache (THA) patients and 16 healthy controls (HC) were exposed to four series of ten electric stimuli at perception threshold, pain threshold and 10% below pain tolerance. The EEG was recorded from three sites, in addition, the EMG from the m. frontalis and m. erector spinae, heart rate and skin conductance were assessed. The CBP patients showed significantly lower pain threshold and pain tolerance values than the HC and the THA patients whereas the THA patients displayed a higher pain tolerance. Habituation was reduced in the CBP group. N150, P260, P300 and N500 were not significantly different between the groups nor were there significant group differences in the peripheral measures. However, since the stimulation intensity was significantly lower in the CBP patients, these data are indicative of both enhanced central and peripheral reactivity. The observed lack of habituation may contribute to the persistence of chronic pain. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
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