期刊
BRITISH JOURNAL OF CANCER
卷 90, 期 11, 页码 2053-2058出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6601705
关键词
leucocyte; tumour; progression; metastasis; angiogenesis
类别
Leucocytes are a major component of the tumour microenvironment. Recent studies have indicated that the infiltration and activity of these host cells are regulated by the tumour to promote its survival and progression. Through the production of an array of growth factors, proteases and angiogenic mediators, leucocytes in the tumour microenvironment promote tumour growth, angiogenesis and metastasis. (C) 2004 Cancer Research UK.
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