期刊
AQUACULTURE
卷 285, 期 1-4, 页码 8-13出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aquaculture.2008.08.013
关键词
Vibrio harveyi; Pathogenicity; Virulent factor; LD50; Extracellular products (ECPs)
资金
- National Fisheries Research and Development Institute, South Korea
- National Research Foundation of Korea [핵06A2504] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Five Vibrio harveyi strains, originally isolated from diseased marine fishes, were virulent for the olive flounder, Paralichthys olivaceus and black rockfish, Sebastes schlegeli. The LD50 value to olive flounder and black rockfish were 2.48 x 10(5)-8.76 x 10(7) and 2.0 x 10(4)-2.52 x 10(6) cfu g(-1) fish, respectively. The extracellular products (ECPs) of the V. harveyi strain were also harmful to olive flounder and black rockfish, with LD50 value of 7.98-11.4 and 1.83-7.7 mu g g(-1) fish, respectively. We analyzed the relationship between toxicity to marine fishes and various virulence factors of V. hareyi. V. harveyi FR2, which was the most pathogenic isolate, showed the maximal effects to the various factors involving the survival ability in the fish serum and fish skin mucus. biofilm formation, and siderophore production. (C) 2008 Elsevier B.V. All rights reserved.
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