期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 48, 期 6, 页码 2292-2294出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.48.6.2292-2294.2004
关键词
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MarA and its homologue, RamA, have been implicated in multidrug resistance (MDR). Ram,4 overexpression in Salmonella enterica serovar Typhimurium and Escherichia coli conferred MDR independently of marA. Inactivation of ramA did not affect the antibiotic susceptibilities of wild-type S. enterica serovar Typhimurium or 15 unrelated clinical MDR isolates. Thus, ramA overexpression is not a common MDR mechanism in Salmonella.
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