期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 48, 期 6, 页码 2314-2317出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.48.6.2314-2317.2004
关键词
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To investigate their potential mechanisms of action, the nucleoside analogue ribavirin and a TLR9 agonist were compared. The CpG oligodeoxynucleotides (ODN) demonstrated strong TLR9-related Th1-type effects, and ribavirin appeared only to mediate signaling in TLR-transfected cells. CpG ODN represent a promising new type of therapeutic drug for hepatitis C or other infectious diseases.
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