期刊
CHEMBIOCHEM
卷 5, 期 6, 页码 832-840出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbic.200300787
关键词
antioxidants; high-throughput screening; immunoassays; natural products; radiolysis
We present a new high-throughput screening method for the selection of powerful water-soluble antiradiation compounds. This method, which uses conventional immunoassay techniques, allowed the capacity of a given compound to protect thymidine from irradiation to be evaluated. By applying this assay to an antioxidant library, we showed for the first time that norbadione A, a well-known mushroom pigment, has pronounced atypical antiradiation properties.
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