期刊
TETRAHEDRON LETTERS
卷 45, 期 27, 页码 5287-5290出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.05.008
关键词
building blocks; tricyclic lactams; gamma-Keto-acid
In order to mimic the complexity of natural products, we designed and obtained with simple synthetic methods, building blocks with 'quaternary chiral centers'. These tricyclic lactams resulted from the reaction of a functional gamma-keto-acid and various commercially available bi-nucleophiles. (C) 2004 Elsevier Ltd. All rights reserved.
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