期刊
JOURNAL OF BONE AND MINERAL RESEARCH
卷 19, 期 7, 页码 1075-1083出版社
WILEY
DOI: 10.1359/JBMR.040301
关键词
insulin-like growth factors; insulin-like growth factor binding proteins; bone density
资金
- NCRR NIH HHS [RR00585] Funding Source: Medline
- NIAMS NIH HHS [AR27065] Funding Source: Medline
The role of the IGFs and IGFBPs on age-related changes in BMD in adult men and women is not well understood. Studying an age-stratified community based sample of 344 men and 276 women, we found higher IGFBP-2 levels to be associated with lower BMD. IGFBP-2, which increases with age in both men and women, was the strongest, most consistent predictor of BMD among the IGF/IGFBPs studied.
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