期刊
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
卷 28, 期 4, 页码 365-378出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.neubiorev.2004.06.002
关键词
behavior; cognition; traumatic brain injury; rats; mice
资金
- NINDS NIH HHS [NS08803] Funding Source: Medline
Traumatic brain injury (TBI) in humans may cause extensive sensorimotor and cognitive dysfunction. As a result, many TBI researchers are beginning to assess behavioral correlates of histologically determined damage in animal models. Although this is an important step in TBI research. there is a need for standardization between laboratories. The ability to reliably test treatments across laboratories and multiple injury models will close the gap between treatment success in the lab and success in the clinic. The goal of this review is to describe and evaluate the tests employed to assess functional outcome after TBI and to overview aspects of cognitive, sensory, and motor function that may be suitable targets for therapeutic intervention. Published by Elsevier Ltd.
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