期刊
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
卷 115, 期 -, 页码 S92-S96出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ejogrb.2004.01.019
关键词
preimplantation embryo metabolism; oxygen consumption; ATP; reactive oxygen species; amino acid turnover
In vitro fertilisation (IVF) has permitted many thousands of couples to conceive world-wide yet is limited by low success rates and a confounding high multiple birth rate due to the transfer of more than one embryo. These problems could be overcome if single embryos of known developmental competence could be selected for replacement. It is clear that current embryo selection methods, which rely on morphological appearance alone, are poor predictors of viability. Metabolism is intrinsic to embryo health and much research has concentrated on developing a non-invasive metabolic marker of developmental competence. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
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