4.7 Article

Cell growing on ion implanted polytetrafluorethylene

期刊

APPLIED SURFACE SCIENCE
卷 314, 期 -, 页码 670-678

出版社

ELSEVIER
DOI: 10.1016/j.apsusc.2014.07.057

关键词

Surface; Plasma; Biocompatibility; PTFE; Cell

资金

  1. Boston Scientific SCIMED Inc. (USA)
  2. Ministry of Science of Germany [WTZ RUS01/225, WTZ RUS00/218]
  3. RFBR [13-01-96009 r_ural_a]
  4. Perm region Government
  5. Alexander von Humboldt Foundation (Germany)

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Polytetrafluorethylene (PTFE and ePTFE) substrates were treated by ion implantation with nitrogen ions of 20 keV energies and 10(13)-10(16) ions/cm(2) ion fluences. The modification of the polymer surface was analyzed by FTIR and XPS spectroscopy, water wetting angle measurements and AFM images. The surface morphology, wettability and chemical activity were changed due to surface modification. The growing of endothelial cells of modified surfaces was improved in comparison with untreated PTFE and ePTFE substrates. The improved cell adherence on the modified surface is based on the improved adhesion of cell proteins. (C) 2014 Elsevier B.V. All rights reserved.

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