期刊
APPLIED SURFACE SCIENCE
卷 273, 期 -, 页码 787-798出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.apsusc.2013.03.001
关键词
Active screen plasma nitriding; Atomic force microscopy; Fibroblast; Interferometry; Nanoindentation; X-ray photoelectron spectroscopy
类别
资金
- EPSRC via a DTA studentship at the School of Metallurgy and Materials, University of Birmingham
- Advantage West Midlands (AWM)
- European Regional Development Fund (ERDF)
- EPSRC [EP/F056311/1]
- University of Leeds
- Engineering and Physical Sciences Research Council [EP/F056311/1] Funding Source: researchfish
- EPSRC [EP/F056311/1] Funding Source: UKRI
Active screen plasma nitriding (ASPN) is a well-established technique used for the surface modification of materials, the result of which is often a product with enhanced functional performance. Here we report the modification of the chemical and mechanical properties of ultra-high molecular weight poly(ethylene) (UHMWPE) using 80:20 (v/v) N-2/H-2 ASPN, followed by growth of 3T3 fibroblasts on the treated and untreated polymer surfaces. ASPN-treated UHMWPE showed extensive fibroblast attachment within 3 h of seeding, whereas fibroblasts did not successfully attach to untreated UHMWPE. Fibroblast-coated surfaces were maintained for up to 28 days, monitoring their metabolic activity and morphology throughout. The chemical properties of the ASPN-treated UHMWPE surface were studied using X-ray photoelectron spectroscopy, revealing the presence of C-N, C=N, and C N chemical bonds. The elastic modulus, surface topography, and adhesion properties of the ASPN-treated UHMWPE surface were studied over 28 days during sample storage under ambient conditions and during immersion in two commonly used cell culture media. (c) 2013 Elsevier B.V. All rights reserved.
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