期刊
JOURNAL OF VIROLOGY
卷 78, 期 13, 页码 7270-7273出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.78.13.7270-7273.2004
关键词
-
类别
RNA interference has been applied for the prevention of virus infections in mammalian cells but has not succeeded in eliminating infections from already infected cells. We now show that the transfection of JC virus-infected SVG-A human glial cells with small interfering RNAs that target late viral proteins, including agnoprotein and VP1, results in a marked inhibition both of viral protein expression and of virus production. RNA interference directed against JC virus genes may thus provide a basis for the development of new strategies to control infections with this polyomavirus.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据