期刊
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
卷 51, 期 1, 页码 126-131出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.jaad.2004.01.058
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Scleromyxedema is a generalized, papular, and sclerodermoid form of lichen myxedematosus associated with monoclonal gammopathy and systemic changes. Despite anecdotal reports of success with various agents, no satisfactory treatments are currently available. We report 3 adult patients with recalcitrant scleromyxedema associated with pamproteinemia who were treated with thalidomide. All 3 patients had marked improvement of the skin lesions and joint mobility after the first 2 months of therapy, with further amelioration after 4 months, and reduction in paraprotein levels.
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