期刊
INFLAMMATORY BOWEL DISEASES
卷 10, 期 4, 页码 436-437出版社
OXFORD UNIV PRESS INC
DOI: 10.1097/00054725-200407000-00017
关键词
Crohn's disease; anti-TNF alpha; infliximab; infection; Pneumocystis firoveci pneumonia; prophylaxis
Anti-TNFalpha therapy is an effective treatment of Crohn's disease. There is an increased risk of infection, including atypical infection associated in infliximab treated patients. We report a case of a young man who developed Pneumocystis jiroveci pneumonia shortly after starting therapy with infliximab. Thus, although rare, prophylaxis against Pneumocystis jiroveci pneumonia might be considered when starting a treatment with infliximab, especially in patients receiving concomitant immunosuppressive agents.
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