期刊
FITOTERAPIA
卷 75, 期 5, 页码 505-509出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2004.03.012
关键词
Cassia obtusifolia; 1,2-dihydroxyanthraquinone; intestinal bacteria; growth response; anthraquinones
1,2-Dihydroxyanthraquinone (1) was isolated from the seed of Cassia obtusifolia through bioassay-guided fractionation. 1,2-Dihydroxyanthraquinone strongly inhibited the growth of Clostridium perfringens and Escherichia coli. Structure-activity relationship revealed that 1,4-dihydroxyanthraquinone (2) and 1,8-dihydroxyanthraquinone (3) had strong growth-inhibition against C. perfringens. In growth-promoting activity, 1,2-, 1,4-, and 1,8-dihydroxy-anthraquinones exhibited strong growth-promoting activity to Bifidobacterium bifidum. (C) 2004 Elsevier B.V. All rights reserved.
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