期刊
JOURNAL OF BONE AND MINERAL RESEARCH
卷 19, 期 7, 页码 1112-1121出版社
WILEY
DOI: 10.1359/JBMR.040319
关键词
celiac disease; osteoporosis; osteoclast; osteoblast; bone resorption
Celiac disease is an autoimmune disorder characterized by atrophy of the intestine villi triggered by ingestion of gluten in genetically susceptible individuals. The association between celiac disease and low BMD has been recognized, but the mechanisms of disturbance are poorly understood. We show imbalance of cytokines relevant to bone metabolism in celiac patients' sera and the direct effect of these sera on in vitro bone cell activity.
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