期刊
OPTICS LETTERS
卷 29, 期 13, 页码 1506-1508出版社
OPTICAL SOC AMER
DOI: 10.1364/OL.29.001506
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- NCRR NIH HHS [P41-RR14075] Funding Source: Medline
- NIBIB NIH HHS [R01-EB002482] Funding Source: Medline
We compare two geometries of sources and detectors for optimizing the diffuse optical imaging resolution of brain activation in humans. Because of limitations in the instruments' dynamic range, most diffuse optical brain activation images have used only nonoverlapping measurements. We demonstrate theoretically and with a human experiment that a simple geometry of sources and detectors can provide overlapping measurements within the limitation of instrumentation: dynamic range and produce an image resolution and localization-accuracy that is twofold better. (C) 2004 Optical Society of America.
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