期刊
TETRAHEDRON LETTERS
卷 45, 期 29, 页码 5755-5758出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.05.032
关键词
aromatic zipper; molecular architecture; super molecule; aromatic stacking; bio-nano materials
A novel thymidine-methyl red conjugate was synthesized and incorporated into oligodeoxyribonucleotides (ODNs). The ODNs containing the conjugate formed a novel nucleic acid-based structural motif, the aromatic zipper, which fastens via the stacking interactions of aromatic residues that are attached to DNA strands. The aromatic zipper can be used to stabilize structural motifs in nucleic acids and their analogues, such as hairpin structures, by fastening their ends. (C) 2004 Elsevier Ltd. All rights reserved.
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