期刊
APPLIED SURFACE SCIENCE
卷 257, 期 13, 页码 5634-5640出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.apsusc.2011.01.062
关键词
Ultrafine-grained titanium; Biocompatibility; Surface modification; Bioactivity; Corrosion
类别
资金
- NSFC-RFBR Cooperation [31011120091]
- National Natural Science Foundation of China [51041004]
- State Key Development Program for Basic Research of China [2007CB936103]
- Fundamental Research Funds for the Central Universities
Bulk ultrafine-grained Ti (UFG Ti) was successfully fabricated by equal-channel angular pressing (ECAP) technique in the present study, and to further improve its surface biocompatibility, surface modification techniques including sandblasting, acid etching and alkali treatment were employed to produce a hierarchical porous surface. The effect of the above surface treatments on the surface roughness, wettability, electrochemical corrosion behavior, apatite forming ability and cellular behavior of UFG Ti were systematically investigated with the coarse-grained Ti as control. Results show that UFG-Ti with surface modification had no pitting corrosion and presented low corrosion rate in simulated body fluids (SBF). The hierarchical porous surface yielded by surface modification enhanced the ability of UFG Ti to form a complete apatite layer when soaked in SBF and promoted osteoblast-like cells attachment and proliferation in vitro, which promises to have a significant impact on increasing bone-bonding ability and reducing healing time when implanted due to faster tissue integration. (C) 2011 Elsevier B. V. All rights reserved.
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