期刊
FEBS LETTERS
卷 571, 期 1-3, 页码 119-123出版社
WILEY
DOI: 10.1016/j.febslet.2004.06.063
关键词
tetrapyrrole biosynthesis; Gun4; Synechocystis 6803
Ycf53 is a hypothetical chloroplast open reading frame with similarity to the Arabidopsis nuclear gene GUN4. In plants, GUN4 is involved in tetrapyrrole biosynthesis. We demonstrate that one of the two Synechocystis sp. PCC 6803 ycf53 genes with similarity to GUN4 functions in chlorophyll (Chl) biosynthesis as well: cyanobacterial gun4 mutant cells exhibit lower Chl contents, accumulate protoporphyrin IX and show less activity not only of Mg chelatase but also of Fe chelatase. The possible role of Gun4 for the Mg as well as Fe porphyrin biosynthesis branches in Synechocystis sp. PCC 6803 is discussed. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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