An emerging role for Kruppel-like factors in vascular biology

The Kruppel-like family of transcription factors play diverse roles regulating cellular differentiation and tissue development. Accumulating evidence supports an important role for these factors in vascular biology. This review examines the current knowledge of this gene family's role in key cell types that critically regulate vessel biology under physiologic and pathologic states. (C) 2004, Elsevier Inc.