期刊
JOURNAL OF NEUROSURGERY
卷 101, 期 2, 页码 227-232出版社
AMER ASSOC NEUROLOGICAL SURGEONS
DOI: 10.3171/jns.2004.101.2.0227
关键词
epiderimoid; cerebellopontine angle; neuroendoscopy; microsurgery
Object. Epidermoid tumors located in the cerebellopontine angle (CPA) are challenging lesions because they grow along the subarachnoid spaces around delicate neurovascular structures and often extend into the middle cranial fossa. The purpose of this study was to determine the value of endoscopic assistance in the microsurgical resection of these lesions, in which total removal is the therapy of choice. Methods. Eight patients harboring an epidermoid tumor of the CPA were treated using an endoscope-assisted microsurgical technique. A retrosigmoid suboccipital approach was used in five patients and a pterional transsylvian approach was chosen in the other three. In four patients the lesion was resected microsurgically and the endoscope was used repeatedly to verify complete tumor removal, whereas most of the tumor mass was removed with the aid of an operating microscope in the other four. Tumor parts extending into other cranial compartments that were not visible through the microscope were removed under endoscopic view by using rigid rod-lens scopes with 30 and 70degrees angles of view. All epidermoids were completely evacuated and the membranes were widely resected. Large tumors occupying both the middle and posterior cranial fossa were removed through a single small opening without enlarging the craniotomy. Permanent hearing loss and permanent hypacusis were observed in one patient each. One patient with facial and one with abducent nerve palsy recovered within 6 and 4 months, respectively. A transient weakness of the chewing muscles was encountered in one patient. Postoperative magnetic resonance imaging revealed no residual tumor in any patient. To date no recurrences have been-observed (follow up range 12-98 months). Conclusions. The endoscope-assisted microsurgical technique enables safe removal even when tumor parts are not visible in a straight line. Tumor extensions into adjacent cranial compartments can be removed with the same approach without retracting neurovascular structures or enlarging the craniotomy.
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