期刊
APPLIED SPECTROSCOPY REVIEWS
卷 46, 期 5, 页码 388-404出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/05704928.2011.565534
关键词
FTIR; leukemia; blood; cell; cancer
资金
- Capes (Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior)
- FAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo)
Fourier transform infrared (FTIR) spectroscopy is an effective and nondestructive method for monitoring cellular alterations. Combining the advantages of FTIR spectroscopy with the challenge of cellular characterization, the main objective of this review is to collect information related to the spectroscopic identification of blood cells, focusing on specific biochemical features of leukemia cells detected through FTIR spectral analysis. Some interesting results obtained by different authors regarding human promyelocytic leukemia, white blood cells, chronic lymphocytic leukemia, and human peripheral blood mononuclear cells are presented. In addition, the characterization of two types of cells, namely, leukemia T and a healthy human blood cells, is reported and the identification of biochemical markers provides important information that, associated with clinical examination, can assist in the diagnosis of diseases.
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