期刊
TRENDS IN PARASITOLOGY
卷 20, 期 8, 页码 355-358出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2004.06.003
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Cryptosporidium is an important pathogen of humans, and a challenging model for the laboratory. The parasite genome sequence, accessible through a comprehensive database, now provides exciting opportunities for urgently needed advances. Comparative genomics, combined with the genetic system in the related parasite Toxoplasma gondii, outlines a detailed Cryptosporidium parvum metabolic map and facilitates cell biological analyses. New targets for Cryptosporidium drug and vaccine development can be identified and validated based on this approach.
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