期刊
JOURNAL OF CHEMOTHERAPY
卷 16, 期 4, 页码 400-403出版社
E I F T SRL
DOI: 10.1179/joc.2004.16.4.400
关键词
endocarditis; enterococcus faecalis endocarditis; ampicillin; ceftriaxone
The case of a patient with highly gentamicin-resistant Enterococcus faecalis endocarditis treated with an ampicillin + ceftriaxone combination is described. We have designed a method to evaluate synergism between the antibacterial activity of patient's serum taken during a given antibiotic regimen (ampicillin) to which another antibiotic (ceftriaxone) is added in vitro. In this patient the two-drug combination was able to stop the bacteremia and prevent the infection of the prosthetic valve.
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