期刊
NATURE
卷 430, 期 7000, 页码 631-639出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nature02621
关键词
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资金
- Intramural NIH HHS [Z01 AG000317-07, Z01 AG000314-07, Z01 AG000312-07, Z01 AG000331-01, Z01 AG000313-07] Funding Source: Medline
Slowly but surely, Alzheimer's disease ( AD) patients lose their memory and their cognitive abilities, and even their personalities may change dramatically. These changes are due to the progressive dysfunction and death of nerve cells that are responsible for the storage and processing of information. Although drugs can temporarily improve memory, at present there are no treatments that can stop or reverse the inexorable neurodegenerative process. But rapid progress towards understanding the cellular and molecular alterations that are responsible for the neuron's demise may soon help in developing effective preventative and therapeutic strategies.
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