期刊
APPLIED RADIATION AND ISOTOPES
卷 94, 期 -, 页码 113-117出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.apradiso.2014.07.015
关键词
[F-18]SFB; PET; Microwave-assisted one-pot synthesis
N-Succinimidyl-4-[F-18]fluorobenzoate ([F-18]SFB) is a potential prosthetic agent for novel tracer development in positron emission tomography (PET). Previously, we reported a microwave-assisted one-pot synthesis of [F-18]SFB with high efficacy. Herein, we reveal an improved and optimized approach based on this former model for producing [F-18]SFB. With optimized approaches, the entire protocol can be completed within 25 min, and [F-18]SFB is generated in satisfactory quality for direct use without further purification via high-performance liquid chromatography. (C) 2014 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据