期刊
FERTILITY AND STERILITY
卷 82, 期 3, 页码 718-722出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2004.03.028
关键词
Varicocele; male infertility; varicocelectomy; microsurgery; recurrence
Objective: To examine the effectiveness of subinguinal microsurgical varicocelectomy in the treatment of persistent or recurrent varicocele. Design: Retrospective chart review. Setting: Urban, tertiary care, academic teaching hospital. Patient(s): Fifty-four men who presented for treatment of persistent or recurrent varicocele. Intervention(s): A single surgeon using an artery and lymphatic sparing subinguinal microsurgical technique with delivery of the testis repaired all varicocele. Main Outcome Measure(s): Preoperative to postoperative changes in semen parameters (volume of ejaculate, sperm concentration, percent motility, percent morphologically normal sperm, total motile sperm concentration), serum hormone levels, and testicular volume. Pregnancy rates and surgical complications were documented. Result(s): Postoperative mean serum T and mean testicular volume increased significantly from prevaricocelectomy levels. Median sperm concentration, percent motility, and total motile sperm per ejaculate improved significantly following recurrent varicocelectomy. Among patients with follow-up over 24 weeks (65%, 35 out of 54), the overall pregnancy rate was 40% (14 out of 35), including 23% (8 out of 35) of pregnancies achieved through natural intercourse, 9% (3 out of 35) with IVF/intracytoplasmic sperm injection, and 9% (3 out of 35) with IUI. Complications such as hydrocele, hematoma, wound infection, and testicular atrophy were not observed during the follow-up period. Conclusion(s): Treatment of persistent or recurrent varicocele using an artery and lymphatic sparing subinguinal microsurgical technique with delivery of the testis improves semen parameters, serum T levels, and testicular volume from preoperative levels without a significant risk of postoperative complications. (C) 2004 by American Society for Reproductive Medicine.
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